An article published this week on the Natural News website reports that the number  of deaths and serious injuries as the result of prescription drugs more than doubled from the first quarter of 2007 to the first quarter of 2008.

According to a report  by the Institute of Safe Medication Practices, researchers found mention of 4,825 fatalities and more than 21,000 serious injuries between January and March, 2008.

The vast majority of the reported fatalities and injuries were attributed to misuse of over the counter pain medications like ibuprofen but 10 drugs accounted for  more than 100 fatalities each, more than 20 percent of the total.

The two single most lethal drugs were the anti-smoking drug varenicline — marketed as Chantix — and the blood thinner heparin. While heparin was responsible for killing a 102 people and injuring 779, the vast majority of these cases were associated with a batch of contaminated medication imported from China. Since the discovery of the tainted drugs, injuries and deaths from heparin have dropped off.

Chantix, in contrast, continues to cause high rates of injury and deaths, accounting for 50 fatalities and 1,001 serious injuries in the first quarter of the year. Since its approval in 2006, the drug has been implicated in 112 fatalities and 3,325 serious injuries. Many of these injuries were self-inflicted and stemmed from the drug’s psychiatric side effects, while others stemmed from seizures, blackouts, loss of consciousness and sudden heart arrhythmia.

If you or a loved one has suffered harm after taking a prescription drug, it is important that you seek the  professional advice of a defective drug attorney.

Chantix has been linked to 10 suicides in the United Kingdom, according to that country’s health regulators.

This is the first time officials at the UK’s Medicines and Healthcare Products Regulatory Agency (MHRA) have revealed the link between Chantix and suicide in that country.  Earlier this year, the U.S. Food & Drug Administration (FDA) said it had linked 37 suicides to Chantix.

Chantix, approved in both the US and Britain in 2006, works by blocking nicotine receptors to the brain. Chantix was the first such nicotine receptor partial agonist approved by the FDA. It was heralded as an alternative to other smoking cessation drugs and nicotine replacement therapy.

But the drug has been the subject of disturbing side effect reports.  In February, the FDA said “it appears increasingly likely that there may be an association between Chantix and serious neuropsychiatric symptoms.” The agency said that it had asked Pfizer to elevate the prominence of safety information regarding suicidal thoughts and other psychiatric problems to the warnings and precautions section of the Chantix prescribing information, or labeling. However, many consumer advocates, including the group Public Citizen, want the FDA to go further and highlight the Chantix suicide risk with black box warning - the agency’s highest safety alert.

In the UK, where Pfizer sells Chantix under the name Champix, the MHRA website says a total of 24 people taking the medication have died, and of those, 10 were suicides. A further 213 claimed they had experienced suicidal thoughts and 407 said they were suffering depression.

The MHRA also says the number of users reporting adverse side effects while using Chantix  has doubled in the past seven months – up from 1,811 in February to 3,541 in September.  The British health watchdog is now  warning doctors and nurses to monitor the effects of the drug on smokers over the New Year, when many will try to kick the habit.

Last December, the European Medicines Agency ruled that the  inserts in boxes of Chantix be updated to include warnings about suicide and depression.